Cannabis for COVID-19: Canadian research claims extracts from the psychoactive drug could fight coronavirus

New Delhi: As various vaccines against the novel coronavirus enter and execute the human trials, researchers are still looking at existing ways and treatments to block and fight COVID-19. According to a recent report, researchers from Canada have found that extracts from Cannabis, also known as marijuana, could help prevent or treat the coronavirus infection. The study was published in peer Journal Preprints. It was conducted by the scientists in April, but the results were released in a non-peer-reviewed, preclinical study. The title of the study was - “In Search of Preventive Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Issues.”

The study was conducted by researchers from Alberta, Canada. They used artificial 3D models of oral, airway and intestinal tissues. High CBD Cannabis sativa extracts were found to modulate ACE2 gene expression and ACE2 protein levels. The results of the study indicated that hemp extracts high in CBD may help block proteins – the ACE-2 receptors, which have been found as the “entry point” for coronavirus into host cells in the body. 

“Angiotensin-converting enzyme 2 (ACE2) has been generally accepted by the scientific community as a receptor required for the entry of SARS-CoV-2 into human cells,” said Dr Igor Kovalchuk, CEO of Pathway Rx and holder of a Health Canada License for Cannabis Research, as reported by AJC. He added, “Our initial findings warrant further investigation but it’s possible that medical cannabis products could become a safe adjunct therapy for the treatment of COVID-19.”  

However, more than 1,000 Cannabis sativa varieties have been screened by Pathway Rx, and only a small number have shown medicinal properties. The research company is further seeking funds to support its efforts to address COVID-19. 

The coronavirus pandemic began in Wuhan, China, last December. The deadly virus has now spread all over the world, infecting more than 4.8 million people around the world, and claiming more than 3,00,000 lives. Various drugs including the anti-malaria drug Hydroxychloroquine, anti-HIV medicines, and others are being tested for treatment against the coronavirus.